As I've said many a time, the Emmys - especially compared with all other award shows - are notoriously hard to predict. Academy members tend to be older, less hip, and sometimes get stuck in their ways. (Remember when John Larroquette won for Night Court four years in a row? He graciously bowed out of the race after that.)

That said, here are my fearless predictions. I say "fearless" because almost no one has a good track record with the Emmys. I may get the big ones right, but I'm not counting on an aced ballot. If I did an Emmy pool, the person who played connect the dots might win by default.
Comedy Series
I'm giving the edge to Modern Family over Glee, even though the latter garnered the most nominations this year. Why? Modern Family is at least as funny as Glee, and it's slightly more conventional and sitcom-y. Either is a worthy candidate. Strangely, the victor the last three years, 30 Rock, is now the dark horse.
Comedy Actor
I think Alec Baldwin is out this year, and Steve Carrell has a better chance next year with his swan song. That leaves it to Tony Shalhoub in his Monk finale, or the very deserving Jim Parsons of The Big Bang Theory. I'll give Parsons the edge, but don't be surprised to see Shalhoub up on stage for a fourth time.
Comedy Actress
Who knew this category would be dominated by Showtime? Last year, Toni Collette of The United States of Tara prevailed, and this year the front-runner appears to be past Sopranos champ Edie Falco. Tina Fey, is it possible you'll actually go home empty-handed this year?
Comedy Supporting Actor
This is a tough one. It's Glee's Chris Colfer against all the Modern Family guys. I'm going out on a limb to say Ty Burrell will narrowly beat Colfer. But don't quote me on that.
Comedy Supporting Actress
Jane Lynch of Glee should have this one in the bag. If not, the Academy will receive hate mail. As they should.
Drama Series
I think Mad Men has the edge, but as dork horses, Dexter or Lost (for its final season) could surprise.
Drama Actor
Oooh, a toughie. Two-time champ Bryan Cranston of Breaking Bad has a shot, but let's give this one to Dexter's Michael C. Hall. He won the Golden Globe and SAG. And hey, a tough cancer fight doesn't hurt his chances.
Drama Actress
Hmmm, will Kyra Sedgwick finally win this year? Methinks not. She might have, if not for the unstoppable Julianna Margulies of The Good Wife. Margulies is likely to be that show's primary winner.
Drama Supporting Actor
I say Terry O'Quinn's amazing John Locke/Smoke Monster hybrid should take the cake in any category. He was scary, funny and touching. How could Emmy voters ask for more? If they falter, the default award will probably go to Aaron Paul of Breaking Bad or Michael Emerson of Lost.
Drama Supporting Actress
I think Mad Men might finally prevail in an acting category here. But for who - Christina Hendricks or the equally worthy Elisabeth Moss? I'll give the edge to Hendricks, though Moss could easily prevail - and Christine Baranski of The Good Wife is a past Emmy favorite.
Other categories:
Made for TV movie: Temple Grandin
Miniseries: The Pacific
Actor in a miniseries or movie: Al Pacino, You Don't Know Jack
Actress in a miniseries or movie: Claire Danes, Temple Grandin
Supporting Actor in a miniseries or movie: David Straitharn, Temple Grandin
Supporting Actress in a miniseries or movie: Susan Sarandon, You Don't Know Jack